I just finished reading Friends star Matthew Perry’s autobiography, “Friends, Lovers, and the Big Terrible Thing.” As you may know, Perry died by drowning in 2023 after injecting ketamine. This dissociative anesthetic has become one of the injection hallucinogens of choice. He was only 53 years old.

In his book, released very shortly before his death, Perry detailed his life as what he calls an “unaccompanied minor,” the term given to children who fly commercially without an adult. He started drinking at the age of 14. At one point in his life, he was taking more than 50 oxycontin pills every day – still not achieving the high craved by his addiction-raddled brain.

Perry called addiction “the big terrible thing,” and it quite literally controlled his life. He had it all at one point – a million bucks a week on America’s number-one TV show, movies, and fame. But Perry suffered from terrible depression, fear, and insecurity. Pills were the only way he could feel, well, as he says it, nothing.

The National Institute of Drug Abuse defines addiction as a chronic, relapsing disorder characterized by compulsive drug seeking and use despite adverse consequences. It causes functional changes to the circuits of the brain responsible for self-control, reward, and stress, lasting long after the addict has stopped drug use.

I may seem out of depth on this topic to those who know me. I’ve been very, very lucky. My father’s side of the family is a tapestry of alcoholism. But, when my grandmother died, Dad was only three years old, and his alcoholic father left. A very religious grandmother and strict aunt raised him, so he didn’t follow in his father’s footsteps. My mother wanted nothing to do with any of it either. So, growing up, I wasn’t exposed to any controlled substances because they weren’t in our home.

As I got older and went to college, then out into the business world, drinking and other drug use are far more prevalent. But I think somewhere down the line, I must have adopted an attitude of, “What do I need that for?” Even in my fraternity days, I was the non-drinker taking keys and getting people home safely. But I could have easily ended up on the pill side of things.

Many people with a substance use disorder start because of prescribed medications due to an injury or surgery. I think I’ve been lucky there, too, given the staggering number of surgeries I had as a child and young adult. I don’t think I ever got past the first two doses of any pain med, and even those were half-strength. I couldn’t handle the “out of control” feeling that euphoric high addicts live their lives trying to get. It was frightening. However, the problem for far too many people is that once they start, regardless of the reason, that may be the ball game.

Far too many people think addiction is about willpower or self-confidence. That’s ridiculous. According to the Cleveland Clinic, the disease of drug addiction may be woven into your DNA. They note that about half of your susceptibility to developing a substance use disorder (SUD) can be hereditary. That makes a person more prone to use alcohol, tobacco products, or drugs such as cocaine, heroin, and opioids. All it might take to put you on the road to addiction is that first high. From there, that’s your life.

As the lovable and hilarious Chandler Bing, Matthew Perry will forever live in our hearts. Sitting on a couch in a New York coffee shop with his five “friends,” he made millions cry laughing. Could he be any funnier? (If you know, you know.) But his passing shocked a generation, and the most painful part is that as sick as he was, it could have been prevented.

As of the time of this writing, five people, including two doctors, have been charged for supplying the drugs that led to Matthew Perry’s death. Hopefully, prosecutors can shut down the supply and save some lives. At least that would be something to give meaning to Perry’s death because, to those of us who admired him, that was the big terrible thing.

Gery Deer is a Greene County resident and columnist. He can be reached at www.gldcommunications.com.